Gene description for TP53 |
Gene name |
tumor protein p53 |
Gene symbol |
TP53 |
Other names/aliases |
BCC7 BMFS5 LFS1 P53 TRP53 |
Species |
Homo sapiens |
Experiment description of studies that identified TP53 in Breast cancer cells |
1
|
Experiment ID | 1230 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
25503107
|
Organism | Homo sapiens |
Experiment description | Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN. |
Authors | Menck K, Scharf C, Bleckmann A, Dyck L, Rost U, Wenzel D, Dhople VM, Siam L, Pukrop T, Binder C, Klemm F. |
Journal name |
J Mol Cell Biol.
|
Publication year | 2015 |
Sample | Breast cancer cells |
Sample name | MCF-7 |
Isolation/purification methods | Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.13-1.22 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140270: EV-METRIC:0%, 33%, 33%
|
|
|
2
|
Experiment ID | 1231 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
25503107
|
Organism | Homo sapiens |
Experiment description | Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN. |
Authors | Menck K, Scharf C, Bleckmann A, Dyck L, Rost U, Wenzel D, Dhople VM, Siam L, Pukrop T, Binder C, Klemm F. |
Journal name |
J Mol Cell Biol.
|
Publication year | 2015 |
Sample | Breast cancer cells |
Sample name | SK-BR-3 |
Isolation/purification methods | Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.13-1.22 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140270: EV-METRIC:0%, 33%, 33%
|
|
|
3
|
Experiment ID | 1678 |
Identified molecule | Protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
34108659
|
Organism | Homo sapiens |
Experiment description | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker |
Authors | Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. |
Journal name |
Nat Cell Biol
|
Publication year | 2021 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 - Exo-rich fractions 7-10 pooled |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 1679 |
Identified molecule | Protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
34108659
|
Organism | Homo sapiens |
Experiment description | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker |
Authors | Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. |
Journal name |
Nat Cell Biol
|
Publication year | 2021 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 - Exo-rich fractions 1-6 pooled |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|